VU0360172 是 mGlu5 受体的正变构调节剂（EC50 = 16 nM；Ki = 195 nM）。
产品描述
VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).
体内活性
VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice[4].
Cas No.
1310012-12-4
分子式
C18H15FN2O
分子量
294.32
别名
VU 0360172;VU-0360172
储存和溶解度
DMSO:83 mg/mL (282.01 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
