Chelidamic acid 是一种最有效的谷氨酸脱羧酶抑制剂(Ki:33 μM)，也是含有吡喃骨架的杂环有机酸，与金属离子有良好的配位能力。

Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.

Chelidonic acid inhibited the glutamate-dependent formation of apoenzyme. Chelidonic acid itself did not promote formation of apoenzyme and did not react with free pyridoxal-P.Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM[1].

138-60-3

C7H5NO5

183.119

白屈氨酸;4-氧代-1,4-二氢-2,6-吡啶二甲酸

DMSO:36 mg/mL (196.59 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years