FTIDC 是非竞争性和选择性的口服变构代谢型谷氨酸受体 1 拮抗剂，对人 mGluR1a 的IC50为 5.8 nM。
产品描述
FTIDC is a highly potent and selective allosteric antagonist of mGluR1 receptors and shows very weak potency against human and rat mGluR5 receptors. The inhibition of FTIDC for mGluR1 receptors is shown to be in noncompetitive manner and displays IC50 values of 5.8 and 3.1 nM for human and mouse mGluR1 expressed in CHO cells respectively.
Cas No.
873551-53-2
分子式
C18H23FN6O
分子量
358.421
储存和溶解度
DMSO:35.8 mg/mL(100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
