产品描述
Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).
体外活性
Foliglurax is a highly selective and potent mGlu4 receptor PAM. It has a marked brain-penetrance feature, which might revolutionize the field of mGlu4 receptor drug targeting in CNS disorders [2].
Cas No.
1883329-51-8
分子式
C23H23N3O3S
分子量
421.51
别名
PXT002331
储存和溶解度
DMSO:5.2 mg/mL (12.34 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
