AWD 131-138 是一种新型的低亲和力部分苯二氮卓受体激动剂，有抗惊厥和抗焦虑作用。

AWD 131-138(Imepitoin) is a new low-affinity partial benzodiazepine receptor agonist. It shows potent anticonvulsant and anxiolytic properties in rodent models.

Cell-based determinations of mTOR inhibition: A high-throughput screening cell-based assay is developed using MDA-MB-468 cells to detect mTORC1 and mTORC2 activity. Cells are exposed for 2 hours to increasing concentrations of AZD8055. At the end of the incubation period, cells are fixed, washed, and probed with antibodies against S473 pAkt or against S235/236 phosphorylated S6 (pS6). Levels of phosphorylation are assessed using an Acumen laser scanning cytometer.

188116-07-6

C13H14ClN3O2

279.72

AWD 131-138;伊匹妥英;ELB-138

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years