EBE-A22 是 PD153035 衍生物，PD153035 能够抑制 ErbB-1 磷酸化，但对 EBE-A22 则无抑制作用。
产品描述
EBE-A22 is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.
激酶实验
GAL-021 is dissolved in DMSO, and final assay concentration of DMSO is 0.1% or less. The effects of GAL-021 (30 μM) on a panel of 55 receptors, transporters, and ion channels are evaluated using radioligand binding analyses. Potential kinase inhibition by GAL-021 (10 μM) is assessed using the Kinase HotSpot Screen where activity of 50 kinases is measured in the presence of adenosine triphosphate (10 μM)[1].
Cas No.
229476-53-3
分子式
C17H16BrN3O2
分子量
374.238
别名
PD153035 Analog 63
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
