UNC2025 2HCl(1429881-91-3(free base))

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

包装	价格(元)
1 mg	询价
2 mg	询价
5 mg	询价
10 mg	询价
25 mg	询价
50 mg	询价
1 mL*10 mM(in DMSO)	询价

UNC2025 2HCl (1429881-91-3(free base)) 是一种有效且具有口服生物利用度的 Mer/FLT3 双重抑制剂，对 Mer/FLT3 的 IC50 为 0.8/0.74 nM。

产品描述

UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.

体内活性

UNC2025 was capable of inhibiting Mer phosphorylation in vivo, following oral dosing as demonstrated by pharmaco-dynamic (PD) studies examining phospho-Mer in leukemic blasts from mouse bone marrow.

Cas No.

T4419

分子式

C28H42Cl2N6O

分子量

549.62

储存和溶解度

DMSO:6.66 mg/mL,Need ultrasonic; in vivo:dissolved in DMSO and then diluted with water (DMSO:water=1:6)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years