产品描述
PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
体外活性
PROTAC BET Degrader-1 is a potent BET degrader based on PROTAC, decreases the level of BRD2, BRD3, and BRD4 proteins in RS4;11 cells at 3-10 nM, and inhibits the growth of this cell line (IC50 of 4.3 nM and 45.5 nM for MOLM-13 cells)[1].
Cas No.
2093386-22-0
分子式
C44H45N11O9
分子量
871.9
储存和溶解度
DMSO:50 mg/mL (57.35 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
