CCI-006 是一种 MLL 重排白血病细胞的选择性抑制剂和化学增敏剂。 它能够抑制线粒体呼吸，造成 MLL-r 白血病细胞亚群中无法克服的线粒体去极化和促凋亡未折叠蛋白反应。
产品描述
CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells. It inhibits mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response in a subset of MLL-r leukemia cells.
Cas No.
292053-42-0
分子式
C15H12N2O5S
分子量
332.33
储存和溶解度
DMSO:83.33 mg/mL (250.74 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
