AS1949490 是选择性SHIP-2抑制剂，其IC50=620 nM。它能够通过上调L6肌管GLUT1基因激活葡萄糖代谢。
产品描述
AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.
Cas No.
1203680-76-5
分子式
C20H18ClNO2S
分子量
371.88
储存和溶解度
DMSO:49 mg/mL (131.76 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
