Trichlormethiazide 是一种口服具有活力的噻嗪类利尿剂，具有降压作用。它能够提高急性肾功能衰竭大鼠的尿量、Na 和 K 排泄，并有改善降低的肌酐清除率。
产品描述
Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.
Cas No.
133-67-5
分子式
C8H8Cl3N3O4S2
分子量
380.64
别名
三氯噻嗪;Trichlormetazid;Naqua;Metahydrin
储存和溶解度
Ethanol:<1 mgml
DMSO:50 mg/mL (131.4 mM)
H2O:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
