hDHODH-IN-1 是有效的人二氢乳清酸脱氢酶抑制剂, 显示出抗炎作用。
产品描述
hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.
体外活性
Human dihydroorotate dehydrogenase (hDHODH) is a class-2 dihydroorotate dehydrogenase.?Because DHODH is required to ensure proliferating-cell viability, inhibitors have been developed to eliminate human DHODH (hDHODH) activity, which is associated with cancers,inflammatory diseases , and autoimmune and multiple sclerosis.
Cas No.
1173715-42-8
分子式
C17H14N2O2
分子量
278.31
储存和溶解度
DMSO:250 mg/mL (898.28 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years