R-IMPP 是抗PCSK9分泌的药物 (IC50=4.8 μM),靶向作用于 80S 核糖体,抑制 PCSK9 蛋白的翻译。
产品描述
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
Cas No.
2133832-83-2
分子式
C24H27N3O2
分子量
389.499
储存和溶解度
DMSO:70 mg/mL(179.9 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years