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(rac)-Antineoplaston A10
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(rac)-Antineoplaston A10图片
CAS NO:77658-84-5
包装与价格:
包装价格(元)
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5 mg询价
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200 mg询价

3-苯基乙酰氨基-2,6-哌啶二酮
Antineoplaston A10
(Rac)-Antineoplaston A10 是 Antineoplaston A10 的消旋体,是一种有抗肿瘤活性的天然产物。Antineoplaston A10 是一种Ras抑制剂,可研究胶质瘤、淋巴瘤、星形细胞瘤和乳腺癌。

产品描述

(Rac)-Antineoplaston A10 is a naturally occurring substance and the first antineoplaston in the human body to be chemically identified. It displayed anti-proliferative action inhibiting cell growth.

体外活性

Antineoplaston A10 (2, 4, 8 mg/ml) inhibited cell proliferation time and dose-dependently in all 6 HCC cell lines. A concentration of 8 mg/ml of Antineoplaston A10 was required to inhibit cell proliferation in KIM-1, KYN-3, HAK-1A, and HAK-1B cells [1]. The HepG2 cells, when incubated with 10 μg/ml of antineoplaston A10, had a cell growth inhibition rate of less than 10% for up to 120 h, while cells incubated with 200 μg/ml of antineoplaston A10 had an inhibition rate of 34.9% at 120 h [2].

Cas No.

77658-84-5

分子式

C13H14N2O3

分子量

246.266

别名

3-苯基乙酰氨基-2,6-哌啶二酮;Antineoplaston A10

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
 
 
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