Ornidazole是一种5-硝基咪唑衍生物,能抗原生动物和厌氧菌。
产品描述
Ornidazole is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.
体外活性
Ornidazole is a 5-nitroimidazole derivative active against protozoa and anaerobic bacteria. It is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms.
Cas No.
16773-42-5
分子式
C7H10ClN3O3
分子量
219.63
别名
Ro 7-0207;奥硝唑;Tiberal;Ornidazolum;NSC 95075
储存和溶解度
Ethanol:41 mg/mL (186.7 mM)
DMSO:41 mg/mL (186.7 mM)
H2O:2 mg/mL (9.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years