产品描述
NU6300 is an inhibitor of the first covalent ATP-competitive CDK2.
体外活性
NU6300 blocks the inhibitor binding site. The effect was time-dependent and relatively slow, with less than 50% reduction of the apparent binding capacity in 20 hr. NU6300 is a covalent CDK2 inhibitor that illustrates the potential of using vinyl sulfones to mediate irreversible inhibition.
Cas No.
2070015-09-5
分子式
C20H23N5O3S
分子量
413.49
储存和溶解度
DMSO:32 mg/mL (77.39 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
