SYN1143 是人 RON 和 c-Met 的有效抑制剂。体外激酶测定表明SYN1143 对人 RON 和 c-Met 的IC50 分别为 9 和 4 nmol/L。
产品描述
AMG-1 is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively.
Cas No.
913376-84-8
分子式
C31H29FN4O5
分子量
556.58
别名
AMG-1;RON-IN-1
储存和溶解度
DMSO:90 mg/mL (161.7 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
