Dihexa 是肝细胞生长因子/c-Met (HGF/c-Met) 系统的激活剂，它与 HGF (Kd = 65 pM) 结合，是肽血管紧张素 IV 的类似物。
产品描述
Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) system,it binds to HGF (Kd = 65 pM),and an analog of the peptide angiotensin IV.
体内活性
Dihexa (2 mg/kg, i.p.) completely reverses scopolamine-induced learning deficits in the latency to find the platform and increases the time spent in the target quadrant in the Morris water maze in rats[1]
Cas No.
1401708-83-5
分子式
C27H44N4O5
分子量
504.672
别名
PNB-0408;Hexanoyl-Tyr-Ile-Ahx-NH2;N-hexanoic-Try-Ile-(6)-amino hexanoic amide
储存和溶解度
DMSO:30 mg/mL (59.45 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
