HAEGTFTSD acetate(926018-45-3 free base) 是 GLP-1 肽的第一个 N 端 1-9 残基。GLP-1 (7-36) 酰胺是前胰高血糖素基因的产物,它是由肠道 L 细胞分泌的,以响应摄入的食物。
产品描述
HAEGTFTSD acetate is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food.
体外活性
The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted from intestinal L-cells, in response to the ingestion of food. GLP-1 exerts multiple actions by stimulating insulin secretion from pancreatic β-cells, in a glucose dependent manner (insulinotropic action). GLP-1 lowers circulating plasma glucagon concentration, by inhibiting its secretion (production) from α-cells. GLP-1 also exhibits properties like stimulation of β-cell growth, appetite suppression, delays gastric emptying and stimulation of insulin sensitivity[1]. The peptide analogs of GLP-1 are useful as glucagon-like peptide 1 receptor agonists[2].
Cas No.
TP1452L1
分子式
C42H61N11O19
分子量
1024.01
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years