Mutated EGFR-IN-1 是用于突变 EGFR 抑制剂设计的有用中间体,例如 L858R EGFR、Exon19 缺失激活突变体和 T790M 抗性突变体。
产品描述
Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
体外活性
Mutated EGFR inhibitor acts as egfr modulators useful for treating cancer.
Cas No.
1421372-66-8
分子式
C25H31N7O
分子量
445.56
别名
Osimertinib analog;AZD9291中间体1
储存和溶解度
DMSO:≥ 75 mg/mL (168.33 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years