产品描述
PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
体外活性
PROTAC B-Raf degrader 1 towards MCF-7, MDA-MB-231, HepG2, LO2 and B16 cells with IC50 values of 2.7 μM, 21.21 μM, 18.70 μM, 41.11μM and 22.68 μM, respectively[1].
Cas No.
2364367-27-9
分子式
C36H37N5O12S
分子量
763.77
储存和溶解度
DMSO:25 mg/mL (32.73 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years