Nelfinavir 是一种口服活性的 HIV-1 蛋白酶抑制剂，用于抑制 HIV 感染,是一种广谱抗癌剂。
产品描述
Nelfinavir is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent.
体外活性
Nelfinavir decreased the viability of a panel of drug-resistant breast cancer cell lines and inhibited the growth of NSCLC xenografts that was associated with induction of ER stress, autophagy, and apoptosis. Nelfinavir is a lead HIV protease inhibitor with pleiotropic effects in cancer cells[1]
Cas No.
159989-64-7
分子式
C32H45N3O4S
分子量
567.79
别名
甲磺酸萘非那韦;AG1341
储存和溶解度
DMSO:100 mg/mL (176.12 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
