ONO-RS-082 是磷脂酶 A 抑制剂。它抑制PLA2的IC50值为1.0 μM，但即使浓度达到 100 μM 也不抑制 PLC。
产品描述
ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor.
体外活性
ONO-RS-082 at 3.5 μM was able to inhibit epinephrine-stimulated thromboxane production in human platelets.?ONO-RS-082 could also disrupt endosome tubule formation and maintenance of the Golgi complex[1].
Cas No.
99754-06-0
分子式
C21H22ClNO3
分子量
371.86
储存和溶解度
DMSO:30mg/mL(80.67mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
