N-Acetyltyramine 是一种群体感应抑制剂，由溶藻弧菌 M3-10 产生。N-Acetyltyramine 可以抑制C. violaceumATCC 12472 的群体感应。它可以逆转阿霉素耐药白血病 P388 细胞的耐药性。

N-Acetyltyramine is the active compound extracted from a fermentation broth of strain M3-10 which produces quorum-sensing inhibitor (QSI) compound. N-Acetyltyramine inhibits Chromobacterium violaceum ATCC 12472 violacein production and virulence factors, such as pyoverdine production, as well as swarming and twitching motilities, produced by Pseudomonas aeruginosa PAO1.

N-Acetyltyramine enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells (IC50 = 0.13 μg/ml)[1].

1202-66-0

C10H13NO2

179.22

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years