L-(+)-Arabinose 能够选择性抑制肠道蔗糖酶，并抑制因蔗糖摄入而导致的血浆葡萄糖提高。
产品描述
L-(+)-Arabinose inhibits intestinal sucrase activity, thereby reducing sucrose utilization, and consequently decreasing lipogenesis.
体外活性
L-(+)-Arabinose is found to be associated with ribose-5-phosphate isomerase deficiency, which is an inborn error of metabolism[1]. L-(+)-Arabinose selectively inhibits intestinal sucrase activity in a noncompetitive manner that suppresses the plasma glucose increase due to sucrose ingestion[1].
体内活性
L-(+)-Arabinose feeding reduced the weights of epididymal adipose tissue in rats. Moreover, plasma insulin and triacylglycerol concentrations were significantly reduced by dietary L-(+)-Arabinose[1]. L-(+)-Arabinose suppresses gluconeogenesis through modulating AMP-activated protein kinase in metabolic disorder mice[2].
Cas No.
5328-37-0
分子式
C5H10O5
分子量
150.13
储存和溶解度
DMSO:40 mg/mL (266.44 mM),Need ultrasonic
H2O:400 mg/mL (2664.36 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
