α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 µg per animal dose, indicating a Th2 response.

922727-14-8

C50H97N3O8

868.32

α-GalCer analog 8;α-Galactosylceramide analog 8

Methanol:Soluble
DMSO:Soluble
DMF:Soluble
Ethanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years