Iopamidol 是一种非离子的X 射线碘化造影剂，可用于多种诊断应用。它具有酰胺和羟基官能团，可用于产生化学交换饱和转移造影剂。

Iopamidol is an organic iodine compound and used as a non-ionic water-soluble radiographic contrast medium.

Iopamidol significantly decreases the rate of atrial contraction to a greater extent than either formulation of iodixanol. Iopamidol decreases papillary muscle force development more than the sodium formulation of iodixanol[3].

Iopamidol increases systolic blood pressure (SBP), mean arterial pressure (MAP), and peak left ventricular pressure (LVP). Iopamidol increases LVP and LV end diastolic pressure to a greater extent than the cationic formulation of iodixanol. Thus iopamidol affects cardiovascular parameters more than iodixanol[3].

Chondrocytes are plated on 96 well plates at a density of 1 x 106 cells/cm2 . After overnight incubation in standard tissue culture conditions, contrast agents (including iopamidol) are introduced to wells in varying concentrations. Following 16 hour incubation with PBS and contrast agents, chondrocyte viability is assessed using the Live/Dead stain kit and quantified using the CellTiter-Glo Luminescent Cell Viability Assay. (Only for Reference)

60166-93-0

C17H22I3N3O8

777.089

B-15000;Iopamiro;SQ-13396;Isovue;Niopam;碘帕醇;Iopamiron

DMSO:93 mg/mL (119.7 mM)
Ethanol:<1 mgml
H2O:92 mg/mL (118.4 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years