PD-1-IN-22 是一种有效的程序性细胞死亡 1 (PD-1)/程序性细胞死亡配体1 (PD-L1) 相互作用的抑制剂,IC50 为 92.3 nM。
产品描述
PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).
体外活性
PD-1-IN-22 dose-dependently elevates interferon-γ(IFN-γ) secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells[1].
Cas No.
2349372-98-9
分子式
C25H25N5O4
分子量
459.5
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years