Caracemide 抑制大肠杆菌的核糖核苷酸还原酶。 Caracemide 可用于抗癌研究。
产品描述
Caracemide inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.
体外活性
Caracemide produces severe central nervous system (CNS) toxicity because of the toxic metabolite, methylisocyanate (MIC). Caracemide inactivates R1 by covalent modification at the substrate-binding site[1].
体内活性
After administration of Caracemide (6.6 mg/kg;i.p.), the mercapturic acid derivative AMCC was identified in rats urine[2].
Cas No.
81424-67-1
分子式
C6H11N3O4
分子量
189.17
别名
卡醋胺;NSC-253272
储存和溶解度
DMSO:95 mg/mL (502.19 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
