Glycol chitosan 是具有亲水性乙二醇支链的壳聚糖衍生物。它抑制大肠杆菌，金黄色葡萄球菌和肠炎链球菌的生长，MIC 值分别为 4 μg/mL，32 μg/m L和<0.5 μg/mL。它可增强 Glycine max Harosoy 63W 细胞的膜通透性和渗漏。

Glycol chitosan is a chitosan derivative with hydrophilic ethylene glycol branches. Glycol chitosan inhibits E. coli, S. aureus, and S. enteritidis growths (MICs: 4 μg/mL, 32 μg/mL, and<0.5 μg/mL). It enhances membrane permeability and leakage in Glycine max Harosoy 63W cells.

The hydrophobic modification of Glycol chitosan is already confirmed, such as Glycol chitosan bearing a 5β-cholanic acid moiety and deoxycholic acid-Glycol chitosan, could self-assemble into nanoparticles, acting as a promising vehicle for hydrophobic drugs and genes [2]. Glycol chitosan can be directly linked with hydrophobic drugs to generate amphiphilic compounds that can also form nanoparticles (NPs) for cell imaging and drug delivery. Glycol chitosan derivatives have been successfully applied to deliver antimicrobial agents and anticancer drugs either by physical encapsulation or chemical conjugation. The use of Glycol chitosan derivatives for cell imaging and drug delivery has several advantages, including superb tumor-homing ability in the case of Glycol chitosan NPs based on enhanced permeability and retention (EPR) effect, low cytotoxicity, ease of chemical modification, great biocompatibility, and biodegradability [1].

123938-86-3

C26H54N4O14

646.732

羟乙基脱乙酰壳多糖;乙二醇壳聚糖

H2O:7.5 mg/mL,Need ultrasonic
DMSO:11.67 mg/mL,Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years