DNA2 inhibitor C5 是竞争性特异性的DNA2 核酸酶活性抑制剂(IC50:20 μM)。它能够抑制DNA 依赖性 ATPase、 DNA2 的核酸酶、解旋酶和 DNA 结合活性。它可用于研究奥正癌症。

DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress and it also is a competitive and specific inhibitor of DNA2 nuclease activity (IC50: 20 μM). DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2.

35973-25-2

C10H6N2O5

234.17

DMSO:31.25 mg/mL (133.45 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years