MARK-IN-4 是一种有效的微管亲和调节激酶(MARK)抑制剂,IC50为 1 nM。抑制 MARK 代表了一种在阿尔茨海默病中阻止神经原纤维缠结病理的潜在方式。
产品描述
MARK-IN-4 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC 50 of 1 nM. Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease [1].
Cas No.
1990492-86-8
分子式
C21H23N7OS
分子量
421.52
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years