Ca2+channel agonist 1 是 N-型钙离子通道激动剂和CDK2的抑制剂，EC50分别为 14.23 μM 和 3.34 μM，可用作运动神经末梢功能障碍的潜在治疗方法。
产品描述
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction.
体外活性
Ca2+ channel agonist 1 (Compound 13d) exhibits a ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine.
Cas No.
1402821-24-2
分子式
C19H26N6O
分子量
354.45
储存和溶解度
DMSO:40 mg/mL (112.85 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
