Ubiquitination-IN-1 是一种有效的泛素化和Cksl-Skp2蛋白互作抑制剂 (IC50=0.17 μM) 抑制剂，增加 p27 水平，可通过阻断肿瘤抑制因子的降解发挥作用。
产品描述
Ubiquitination-IN-1 is an inhibitor of ubiquitination and Cksl-Skp2 protein-protein interaction (IC50: 0.17 μM).
体外活性
Ubiquitination-IN-1 inhibits A549 and HT1080 cells (IC50s of 0.91 and 0.4 μM, respectively).
Cas No.
1819330-15-8
分子式
C21H14F3N3O2S
分子量
429.42
储存和溶解度
DMSO:60 mg/ml (139.72 mM),Need ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
