2-Pyridinecarboxamide,4-[[6-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]iminomethyl]amino]-3-pyridinyl]oxy]-N-methyl-

位置：首页 > 产品库 > 2-Pyridinecarboxamide,4-[[6-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]iminomethyl]amino]-3-pyridinyl]oxy]-N-methyl-

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2136278-38-9

包装与价格：

包装	价格(元)
1 mg	询价
5 mg	询价
10 mg	询价
25 mg	询价
50 mg	询价
100 mg	询价

NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base)
2-Pyridinecarboxamide, 4-[[6-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]iminomethyl]amino]-3-pyridinyl]oxy]-N-methyl-

2-Pyridinecarboxamide, 4-[[6-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]iminomethyl]amino]-3-pyridinyl]oxy]-N-methyl-是一种新的芳基胍抑制剂。

产品描述

2-Pyridinecarboxamide, 4-[[6-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]iminomethyl]amino]-3-pyridinyl]oxy]-N-methyl- is a novel aryl-guanidino inhibitor.

体外活性

Jurkat and HUT78 cells was markedly inhibited by DCZ3301 treatment in a time- and dose- dependent manner, IC50 values for Jurkat and HUT78 cells were 3.02 μM and 9.42 μM, respectively, after 2-Pyridinecarboxamide, 4-[[6-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]iminomethyl]amino]-3-pyridinyl]oxy]-N-methyl- treatment for 48 h.

Cas No.

2136278-38-9

分子式

C20H16ClF3N6O2

分子量

464.83

别名

NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base);2-Pyridinecarboxamide, 4-[[6-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]iminomethyl]amino]-3-pyridinyl]oxy]-N-methyl-

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years