Trometamol 是一种在生理范围内控制 pH 值的有效胺类化合物，也是一种低毒性的生物惰性氨基醇，可以在体内和体外缓冲二氧化碳和酸。

Trometamol is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostaglandins.

The drug is rapidly eliminated by the kidney; 75% or more appears in the urine after eight hours. Urinary excretion continues over a period of three days. The maximum daily dose is 15 mmol/kg for an adult. In large doses, trometamol may induce respiratory depression and hypoglycemia. [1]

77-86-1

C4H11NO3

121.136

Tromethamine;三(羟甲基)氨基甲烷;缓血酸铵;Trometamol

H2O:198.1 mM
DMSO:16.5 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years