Tebipenem 是一种口服碳青霉烯类抗生素。 它对革兰氏阳性和阴性细菌具有广谱活性。

Tebipenem is an orally available carbapenem antibiotic. It displays broad-spectrum activity against Gram-positive and -negative bacteria.

Tebipenem shows potent activity against B. pseudomallei (MIC50 and MIC90: both 2 mg/L). Tebipenem displays slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin (apparent Km and kcat: 0.8 μM and 0.03 min-1, respectively). Tebipenem shows good activity against S. pneumoniae, with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates [1][2][3].

161715-21-5

C16H21N3O4S2

383.49

Tebipenem

DMSO:30 mg/mL (78.23 mM),Need ultrasonic
H2O:6 mg/mL (15.65 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years