Compound 35 是埃博拉 (Mayinga) 和马尔堡 (安哥拉) 传染性病毒的优良抑制剂。
产品描述
Compounds 35 are superior inhibitors of Ebola (Mayinga) and Marburg (Angola) infectious viruses.
体外活性
Compounds 35 are superior inhibitors of Ebola (Mayinga) and Marburg (Angola) infectious viruses. Compounds 35 have shown good metabolic stability in plasma and liver microsomes (rat and human), and 32 did not inhibit CYP3A4 nor CYP2C9. These 4-(aminomethyl)benzamides are suitable for further optimization as inhibitors of filovirus entry, with potential to be developed as therapeutic agents for the treatment and control of Ebola virus infections.
Cas No.
T8686
分子式
C25H30F3N3O2
分子量
461.52
别名
Compound 35
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
