Delpazolid 是一种恶唑烷酮类新型抗生素，能抑制MSSA和MRSA的生长，对它们的MIC90值都为 2 μg/mL。

Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.

1219707-39-7

C14H17FN4O3

308.313

LCB01-0371;Delpazolid

DMSO:30 mg/mL (97.30 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years