Nebracetam hydrochloride 是促智 M1-毒蕈碱的激动剂。 它诱导细胞内 Ca2+ 浓度升高， EC50 为 1.59 mM。

Nebracetam hydrochloride is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i.

Nebracetam involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms.

Nebracetam (WEB 1881 FU), a new nootropic candidate, was able to correct this scopolamine-induced disruption of spatial cognition at the dose of 10 mg/kg, p.o in male Wistar rats weighing 200-250 g [2].

1177279-49-0

C12H17ClN2O

240.73

WEB 1881 FU hydrochloride;Nebracetam hydrochloride

DMSO:99 mg/mL (411.24 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years