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BODIPY FL prazosin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:175799-93-6
包装与价格:
包装价格(元)
5 mg询价
50 mg询价
100 mg询价

BODIPY FL prazosin 是一种荧光 α1-肾上腺素α1-adrenergic拮抗剂,对 α1a-AR 和 α1b-AR 的Ki值分别为 14.5、43.3 nM. BODIPY FL prazosin 也是一种荧光配体,激发和发射波长分别为 485 和 535 nm。BODIPY FL prazosin 可用于研究 α1 -肾上腺素受体亚型的亚细胞定位差异 。

产品描述

BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with K i values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively. BODIPY FL prazosin also is a fluorescent ligand with the excitation and emission wavelengths are 485 and 535 nm, respectively. BODIPY FL prazosin can be used for study the differences in the subcellular localization of α1-adrenoceptor subtypes [1] [2] [3].

体外活性

BODIPY FL prazosin (10 nM; 30 min at room temperature in 100 μl; COS-7 cells) shows Affinity of various α1-AR ligands with K i values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively [1]. BODIPY FL prazosin (100 nM, 30 min) can be used as molecular probe for the Visualization of the non-adrenoceptor binding site of α1-adrenergic drugs in erythroleukemia cells [3].

Cas No.

175799-93-6

分子式

C28H32BF2N7O3

分子量

563.41

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
 
 
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