Tolazoline hydrochloride 是一种 α 肾上腺素受体抑制剂。
产品描述
Tolazoline is a non-selective competitive α-adrenergic receptor antagonist used in treatment of persistent pulmonary hypertension of the newborn.
体内活性
在新生儿持续性肺动脉高压（PPHN）中,Tolazoline作为肺血管扩张剂,能够降低肺血管阻力（PVR）和肺动脉压力。在人体桡动脉中,Tolazoline能够阻断α-肾上腺素活性, 从而显著对抗血管痉挛。
Cas No.
59-97-2
分子式
C10H13ClN2
分子量
196.68
别名
Imidaline hydrochloride;Imidaline (hydrochloride);NSC35110 (hydrochloride);苯甲唑啉盐酸盐;Tolazoline HCl;Benzidazol hydrochloride;Tolazoline hydrochloride
储存和溶解度
H2O:36 mg/mL (183 mM)
DMSO:37 mg/mL (188.1 mM)
Ethanol:37 mg/mL (188.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
