7-Hydroxyisoflavone 有体外抗肠道病毒 71作用。

7-Hydroxyisoflavone against Enterovirus 71 in vitro.

7-hydroxyisoflavone was active against EV71.?7-Hydroxyisoflavone exhibited strong antiviral activity against three different EV71 strains.?The 50% inhibitory concentration range was between 3.25 and 4.92 μM by cytopathic effect assay.?7-Hydroxyisoflavone could reduce EV71 viral RNA and protein synthesis in a dose-dependent manner.?Time course study showed that treatment of Vero cells with 7-hydroxyisoflavone at indicated times after EV71 inoculation (0-6 h) resulted in significant antiviral activity[1].

13057-72-2

C15H10O3

238.242

7-Hydroxyisoflavone

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years