P110 TFA 是一种 Dynamin-related protein 1 (Drp1) 抑制剂，抑制 Drp1 GTPase 活性。
产品描述
P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity.
体外活性
P110 TFA Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins.?Inhibits mitochondrial fission, dysfunction and reactive oxygen species (ROS) production in vitro.?Reduces programmed cell death and improves cell viability by protecting mitochondrial integrity.?Reduces mitochondrial fragmentation and mitochondrial ROS production in mouse model of Parkinson's disease.?Cell permeable.
Cas No.
TP1947L
分子式
C102H180F3N45O27
分子量
2525.8
别名
P110 TFA
储存和溶解度
H2O:50mg/mL,Need ultrasonic
DMSO:50mg/mL,Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
