TP0586532 是有效的non-hydroxamate LpxC抑制剂 (IC50=0.101 μM)。TP0586532具有低心血管风险的特点，对肺炎克雷伯菌有效，包括耐药菌株。
产品描述
TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.
体外活性
TP0586532 is an inhibitor of UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) with an IC50 of 0.101 μM[1].
Cas No.
2427584-96-9
分子式
C26H28N4O4
分子量
460.52
别名
TP0586532
储存和溶解度
DMSO:50 mg/mL (108.57 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
