(Rac)-CFT7455 是一种IkaROS/Aiolos降解剂，通过泛素蛋白酶体途径起作用，对 NCIH929.1 细胞的GI50为 0.05 nM。(Rac)-CFT7455 是具有抗癌活性的 CFT7455 的外消旋异构体。
产品描述
(Rac)-CFT7455 is a zinc finger transcription factors Ikaros (IKZF1) and Aiolos (IKZF3) degrader, acting via the ubiquitin proteasome pathway, with a GI 50 of 0.05 nM for NCIH929.1 cells. (Rac)-CFT7455 is the racemic isomer of CFT7455 which is a IKZF1/IKZF3 degrader with anticancer activity [1] [2].
Cas No.
2504233-68-3
分子式
C28H27N3O4
分子量
469.53
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
