Tegaserod maleate 是选择性5-HT4受体的部分激动剂和5-HT2B受体的拮抗剂，用于治疗肠易激综合征和便秘。

Tegaserod is a 5-HT4 agonist manufactured by Novartis and used for the management of irritable bowel syndrome and constipation. Its use was the only drug approved by the United States Food and Drug Administration to help relieve the abdominal discomfort, bloating and constipation associated with irritable bowel syndrome. On March 30, 2007, the U.S. Food and Drug Administration requested that Novartis withdraw Zelnorm from shelves. The FDA alleges a relationship between prescriptions of the drug and increased risks of heart attack or stroke.

189188-57-6

C20H27N5O5

417.466

马来酸替加色罗;HTF-919;SDZ-HTF-919;Tegaserod maleate

DMSO:35 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years