Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
产品描述
Albuterol stimulates beta2-adrenergic receptors in the lungs, thereby activating the enzyme adenylate cyclase that catalyzes the conversion of ATP to cyclic-3', 5'-adenosine monophosphate (cAMP). Albuterol Sulfate is the sulfate salt of the short-acting sympathomimetic agent albuterol, a 1:1 racemic mixture of (R)-albuterol and (S)-albuterol with bronchodilator activity. Increased cAMP concentrations relax the bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell mediator release, especially from mast cells. To a lesser extent, albuterol stimulates beta1-adrenergic receptors, thereby increasing the force and rate of myocardial contraction.
Cas No.
18559-94-9
分子式
C13H21NO3
分子量
239.31
别名
AH-3365;沙丁胺醇;Albuterol;Salbutamol
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years