Flunarizine dihydrochloride 是Na+/Ca2+(T 型) 通道双重阻滞剂。它也是D2多巴胺受体拮抗剂。它具有用于扩张外周血管和预防偏头痛的潜力。

Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine hydrochloride is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.

30484-77-6

C26H28Cl2F2N2

477.42

KW-3149;盐酸氟桂利嗪;R14950;Flunarizine 2HCl;Flunarizine dihydrochloride

DMSO:23.9 mg/mL (50 mM)
Ethanol:2.4 mg/mL (5 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years