Lasmiditan succinate 是一种 5-ht (1F) 受体激动剂，作用于中枢神经系统（Ki 值为 2.21 nM）。
产品描述
Lasmiditan succinate is a 5-ht (1F) receptor agonist acting on the central nervous system(Ki value of 2.21 nM).
体内活性
Lasmiditan, a novel serotonin1F receptor agonist, showed specific affinity in vitro for the receptor without any vasoconstrictive action and inhibited markers associated with electrical stimulation of trigeminal ganglion in migraine animal models[1].
Cas No.
439239-92-6
分子式
C42H42F6N6O8
分子量
872.822
别名
Lasmiditan succinate
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
